Arterial remodeling influences the development of intimal hyperplasia after stent implantation.
J Am Coll Cardiol
; 37(1): 70-5, 2001 Jan.
Article
em En
| MEDLINE
| ID: mdl-11153775
ABSTRACT
OBJECTIVES:
We examined whether preinterventional arterial remodeling influenced the interventional results after stenting.BACKGROUND:
Arterial remodeling is seen in atherosclerotic lesions, and it may play an important role in the early stage of atherosclerosis.METHODS:
We examined 113 lesions that underwent elective stenting using tubular slotted stents under intravascular ultrasound guidance. The lesions were divided into three groups--adequate, intermediate and inadequate remodeling group--according to preinterventional arterial remodeling. The patients were subjected to coronary angiography and intravascular ultrasound evaluation on average 6.4 months after stenting.RESULTS:
At baseline and immediately after stenting, there were no differences in quantitative angiographic analysis among remodeling groups. However, the plaque cross-sectional area (CSA) in the minimal lumen CSA at preintervention and intimal hyperplasia CSA at follow-up were significantly larger in the adequate remodeling group than in the inadequate remodeling group. The restenosis rate of stenting for the lesions with inadequate arterial remodeling was very low (9.4%). A significant positive correlation was found between preinterventional plaque CSA and intimal hyperplasia CSA at follow-up (r = 0.47, p < 0.0001). Moreover, remodeling index significantly correlated with relative intimal hyperplasia CSA (r = 0.28, p < 0.01).CONCLUSIONS:
Preinterventional arterial remodeling influenced the development of intimal hyperplasia after stenting.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doença da Artéria Coronariana
/
Angioplastia Coronária com Balão
/
Stents
/
Túnica Íntima
/
Ultrassonografia de Intervenção
/
Vasos Coronários
/
Displasia Fibromuscular
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Am Coll Cardiol
Ano de publicação:
2001
Tipo de documento:
Article