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Oxidative degradation of pharmaceuticals: theory, mechanisms and inhibition.
Hovorka, S; Schöneich, C.
Afiliação
  • Hovorka S; Department of Pharmaceutical Chemistry, The University of Kansas, 2095 Constant Avenue, Lawrence, Kansas 66047, USA.
J Pharm Sci ; 90(3): 253-69, 2001 Mar.
Article em En | MEDLINE | ID: mdl-11170019
ABSTRACT
Oxidation is a common pathway for drug degradation in liquid and solid formulations. The present article reviews mechanistic details of autoxidation and chain oxidation processes, as well as the oxidation of selected functional groups commonly affected in drugs.
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas Idioma: En Revista: J Pharm Sci Ano de publicação: 2001 Tipo de documento: Article
Buscar no Google
Imprimir
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PubMed Links

Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas Idioma: En Revista: J Pharm Sci Ano de publicação: 2001 Tipo de documento: Article