The library of p-nitrophenyl esters of oligopeptides as a model to study the anticancer drug-peptide conjugates activated during tumor angiogenesis.
Acta Pol Pharm
; 57 Suppl: 143-6, 2000 Nov.
Article
em En
| MEDLINE
| ID: mdl-11293248
ABSTRACT
An indexed library of oligopeptide p-nitrophenyl esters immobilized via methoxy-1,3,5-triazine scaffold on the cellulose support, was synthesized by the step by step procedure and by segment coupling, involving 2-chloro-4,6-dimethoxy-1,3,5-triazine as a condensing reagent. The substrate specificity towards homogenate supernatant of mouse lung cancer LL2 cells has been studied.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oligopeptídeos
/
Biblioteca de Peptídeos
/
Neovascularização Patológica
/
Antineoplásicos
Limite:
Animals
Idioma:
En
Revista:
Acta Pol Pharm
Ano de publicação:
2000
Tipo de documento:
Article