Adverse effect of dentine bonding agent on the oral mucosa of guinea pigs.
J Oral Rehabil
; 28(1): 88-94, 2001 Jan.
Article
em En
| MEDLINE
| ID: mdl-11298914
ABSTRACT
The purpose of present study was to determine the possibility of nebulous discoloration of the oral mucosa of guinea pigs as a result of the application of dentine bonding agents. The materials used were the Clearfil Photo Bond (CPB) system's mixture agent, universal agent and catalyst agent. Four types of experimental catalysts were used. In male albino guinea pigs weighing 300-500 g, oral mucosa irritation tests were performed in accordance with the guidelines of the Cosmetic, Toiletry and Fragrance Association (CTFA). Macroscopical findings on the oral mucosa showed that there was strong nebulous discoloration immediately after application of CPB mix and CPB catalyst and throughout the experimental periods. However, CPB without 10-methacryloxdecyl dihydrogen phosphate (MDP) did not produce noticeable nebulous discoloration and inflammation. The CPB mix caused pathological changes, such as paraketosis and hyperkeratosis on the endepidermis of the mucosa, immediately after its application.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Adesivos Dentinários
/
Cimentos de Resina
/
Mucosa Bucal
Limite:
Animals
Idioma:
En
Revista:
J Oral Rehabil
Ano de publicação:
2001
Tipo de documento:
Article