Inhibitors of platelet lipoxygenase from Ponkan fruit.
Phytochemistry
; 56(7): 729-32, 2001 Apr.
Article
em En
| MEDLINE
| ID: mdl-11314960
ABSTRACT
An activity-guided separation for inhibitors of rat platelet 12-lipoxygenase led to the isolation of two compounds, 4-O-feruloyl-5-O-caffeoylquinic acid (IC50; 5.5 microM) and methyl 4-O-feruloyl-5-O-caffeoylquinate (IC50; 1.9 microM) from the peel of Ponkan fruit (Citrus reticulata). The complete structure of each phenolic ester was determined by NMR spectroscopy [1H and 13C NMR spectra, 1H-1H correlation spectroscopy (COSY), 1H-detected heteronuclear multiple quantum coherence (HMQC), and heteronuclear multiple bond connectivity (HMBC) spectroscopies] and other spectral methods.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Plaquetas
/
Araquidonato 12-Lipoxigenase
/
Citrus
/
Inibidores de Lipoxigenase
/
Ácidos Cicloexanocarboxílicos
Limite:
Animals
Idioma:
En
Revista:
Phytochemistry
Ano de publicação:
2001
Tipo de documento:
Article