Synthesis of a divalent glycoside of an alpha-galactosyl disaccharide epitope involved in the hyperacute rejection of xenotransplantation.
Carbohydr Res
; 334(4): 289-94, 2001 Sep 07.
Article
em En
| MEDLINE
| ID: mdl-11527530
ABSTRACT
3,6-dioxaoct-1,8-diyl di-(3-O-alpha-D-galactopyranosyl-beta-D-galactopyranoside) was synthesized for use in research on hyperacute rejection of xenotransplantation. The trichloroacetate method was successfully applied to form stereoselectively the alpha-D-galactosyl linkage under mild reaction conditions and a simple procedure. The divalent O-glycoside was formed from the corresponding trichloroacetimidate in one step with reasonable yield.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transplante Heterólogo
/
Dissacarídeos
/
Galactose
/
Glicosídeos
/
Rejeição de Enxerto
/
Epitopos
Idioma:
En
Revista:
Carbohydr Res
Ano de publicação:
2001
Tipo de documento:
Article