Immunocytochemistry in effusion cytology: a contemporary review.
Cancer
; 93(5): 293-308, 2001 Oct 25.
Article
em En
| MEDLINE
| ID: mdl-11668464
ABSTRACT
BACKGROUND:
Cytology plays a pivotal role in the diagnosis of pleural effusions. In many cases, immunocytochemistry (ICC) is required to elucidate the etiology of the atypical cells. Effusions are samples that present unique problems for ICC. To date there is no standardization of ICC methods for effusions and cytology in general.METHODS:
The authors review the most commonly used cytologic preparations, fixatives, and antibodies used in effusion ICC.RESULTS:
Through the utilization of cell block preparations and a panel of antibodies appropriate for the differential diagnosis in question, ICC conditions utilized in surgical pathology can be most closely replicated.CONCLUSIONS:
ICC may provide reliable insights into various diagnostic dilemmas in effusion cytology, provided that laboratory standardization practices are followed.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Imuno-Histoquímica
/
Derrame Pleural Maligno
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
Cancer
Ano de publicação:
2001
Tipo de documento:
Article