Psychological screening of children for participation in nontherapeutic invasive research.
Arch Pediatr Adolesc Med
; 155(11): 1197-203, 2001 Nov.
Article
em En
| MEDLINE
| ID: mdl-11695927
ABSTRACT
BACKGROUND:
The need for children to participate in research has raised concerns about ethical issues surrounding their participation.OBJECTIVES:
To describe a protocol of preresearch psychological screening and postresearch outcomes and to present the results of the screening process for a nontherapeutic, invasive research study. DESIGN ANDSETTING:
Descriptive study carried out at The University of Iowa Hospitals and Clinics, Iowa City.PARTICIPANTS:
Twenty-eight children (mean age, 10.6 years) were screened, with 4 not completing the research study and another 4 unavailable for psychological follow-up. MAIN OUTCOMEMEASURES:
Prescreening interviews with parent and child and screening measures of appropriate child cognitive abilities and behavior; postscreening parent and child questionnaires.RESULTS:
Of the 4 children who did not complete the research study, 3 were identified with increased anxiety during the screening and were advised to not participate in the study. The primary motivator for participation was monetary reimbursement (14 parents [82%]; 15 children [75%]), followed by altruistic reasons (10 parents [59%]; 4 children [20%]). Before participating, none of the children reported concerns related to participating in the study. However, on follow-up, 9 (45%) of the children reported that they had had concerns before participating. Follow-up assessment showed that parents underestimated their children's concerns related to sexual development assessment and intravenous insertion.CONCLUSIONS:
Children with increased anxiety may not be appropriate participants in potentially anxiety-provoking research. Children's reports of concerns may change from preparticipation to postparticipation, and discrepancies may exist between parent and child reports of concerns with research participation. Further research is needed to ensure children's safe participation in research.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Estresse Psicológico
/
Psicologia da Criança
/
Seleção de Pacientes
/
Experimentação Humana
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Guideline
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
Aspecto:
Ethics
Limite:
Adolescent
/
Child
/
Female
/
Humans
/
Male
País/Região como assunto:
America do norte
Idioma:
En
Revista:
Arch Pediatr Adolesc Med
Ano de publicação:
2001
Tipo de documento:
Article