Advanced diagnostic methods in oral and maxillofacial pathology. Part I: molecular methods.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
; 92(6): 650-69, 2001 Dec.
Article
em En
| MEDLINE
| ID: mdl-11740483
ABSTRACT
The practice of pathology is currently undergoing significant change, in large part due to advances in the analysis of DNA, RNA, and proteins in tissues. These advances have permitted improved biologic insights into many developmental, inflammatory, metabolic, infectious, and neoplastic diseases. Moreover, molecular analysis has also led to improvements in accuracy of disease diagnosis and classification. It is likely that, in the future, these methods will increasingly enter into the day-to-day diagnosis and management of patients. The pathologist will continue to play a fundamental role in diagnosis and will likely be in a pivotal position to guide the implementation and interpretation of these tests as they move from the research laboratory into diagnostic pathology. The purpose of this 2-part series is to provide an overview of the principles and applications of current molecular biologic and immunologic tests. Part I will discuss the biologic fundamentals of DNA, RNA, and proteins and the methods that are currently available or likely to become available to the pathologist in the next several years for their isolation and analysis in tissue biopsies.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Patologia Bucal
/
Técnicas de Diagnóstico Molecular
/
Diagnóstico Bucal
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
Ano de publicação:
2001
Tipo de documento:
Article