[Therapeutic application for the aged with CML].
Nihon Rinsho
; 59(12): 2407-9, 2001 Dec.
Article
em Ja
| MEDLINE
| ID: mdl-11766347
ABSTRACT
Therapeutic application for elderly CML patients had been restricted to use of alkylating or antimetabolite agents. In order to improve quality of life in the aged with CML interferon-alpha therapy is now first choice for treatment of elderly chronic phase of CML patients under appropriate informed consent. This treatment provided long term survival with cytological and cytogenetic responses even in the aged. In elderly patients attention has to be paid for the occurrence of side effects such as psychological changes. Further studies are on going in special reference to molecularly targeted therapy, i.e. a specific inhibitor of tyrosine kinase, or non-myeloablative stem cell transplantation.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Qualidade de Vida
/
Leucemia Mieloide de Fase Crônica
/
Consentimento Livre e Esclarecido
Aspecto:
Patient_preference
Limite:
Aged
/
Humans
Idioma:
Ja
Revista:
Nihon Rinsho
Ano de publicação:
2001
Tipo de documento:
Article