Cerebral vasoconstriction and stroke after use of serotonergic drugs.
Neurology
; 58(1): 130-3, 2002 Jan 08.
Article
em En
| MEDLINE
| ID: mdl-11781419
ABSTRACT
Serotonin (5-hydroxytryptamine) is a potent vasoconstrictor amine. The authors report three patients who developed thunderclap headache, reversible cerebral arterial vasoconstriction, and ischemic strokes (i.e., the Call-Fleming syndrome). The only cause for vasoconstriction was recent exposure to serotonergic drugs in all patients, and to pseudoephedrine in one patient. These cases, and the literature, suggest that the use of serotonin-enhancing drugs can precipitate a cerebrovascular syndrome due to reversible, multifocal arterial narrowing.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vasoconstrição
/
Artérias Cerebrais
/
Isquemia Encefálica
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Agonistas do Receptor de Serotonina
Limite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Neurology
Ano de publicação:
2002
Tipo de documento:
Article