Effects of hokoei-to (pugongying-tang), a Kampo formula, on monoamine content in brain regions and mitogenic activity of splenic lymphocytes in ovariectomized mice.
Am J Chin Med
; 29(3-4): 433-43, 2001.
Article
em En
| MEDLINE
| ID: mdl-11789586
ABSTRACT
Hokoei-to (pugongying-tang) is one of the Kampo formulae clinically used for gynecological disturbances such as lack of lactation and mammary swelling. We investigated the effect of hokoei-to on the nervous and immune systems in ovariectomized mice as a climacteric disorder model. Hokoei-to suppressed the decrease of monoamines in the ventral hippocampus and dorsal hippocampus of ovariectomized mice. It was shown that the hokoei-to could improve the metabolic turnover of dopamine. The mitogenic activity of lymphocytes in the spleen was reduced after ovariectomy; a suppression of this reduced activity was observed in the group given hokoei-to.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Encéfalo
/
Medicamentos de Ervas Chinesas
/
Linfócitos
/
Monoaminas Biogênicas
/
Mitógenos
Limite:
Animals
Idioma:
En
Revista:
Am J Chin Med
Ano de publicação:
2001
Tipo de documento:
Article