[Paclitaxel (Taxol) in chemotherapy of head and neck cancer--just another proposal or breakthrough?]. / Paklitaksel (Taxol) w chemioterapii nowotworów glowy i szyi--kolejna propozycja czy przelom?

The examples of so far application of taxol in head and neck cancer are not completely clear. This is the first representative of a totally new group of cytostatics known as taxones. Presently, paclitaxel (TAXOL) is the anti-cancer drug commonly used in ovary cancer patients, resistant to platinum analogues. Taxones have the different functioning than the other anti-cancer drugs. They are responsible for originating microtubules and their further stabilisation. Moreover, paclitaxel (TAXOL) is a chemical compound sensitizing tumor cells for ionizing radiation. The authors are trying to specify the role of taxones nowadays and for the future use.