Human uterodomes (pinopods) do not display pinocytotic function.
Hum Reprod
; 17(8): 1980-6, 2002 Aug.
Article
em En
| MEDLINE
| ID: mdl-12151424
ABSTRACT
BACKGROUND:
The term 'pinopod' or 'pinopode' has been used indiscriminately since the 1970s to describe most apical structures on uterine epithelial cells and as such suggests a cross species structural functionality. This study looks at the apical cellular protrusions in rats and humans and compares their pinocytotic ability.METHODS:
We have utilized standard tracer techniques in an attempt to determine the functionality of the uterine surface protrusions in the human based on results reported in rats.RESULTS:
Pinopods in rat tissue demonstrated tracer uptake, but no tracer uptake in the apical protrusions of human uterine epithelium was evident.CONCLUSIONS:
These findings indicate that the uterine surface protrusions observed in the human are not pinocytotic and therefore probably perform a function different from similar structures observed in rats and mice. This highlights the need to alter nomenclature from pinopods to uterodomes.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pinocitose
/
Útero
Limite:
Adult
/
Animals
/
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Hum Reprod
Ano de publicação:
2002
Tipo de documento:
Article