Time dependent responses of glycolytic intermediates in a detailed glycolytic model of Lactococcus lactis during glucose run-out experiments.
Mol Biol Rep
; 29(1-2): 157-61, 2002.
Article
em En
| MEDLINE
| ID: mdl-12241048
ABSTRACT
Glucose addition and subsequent run-out experiments were compared to simulations with a detailed glycolytic model of Lactococcus lactis. The model was constructed largely on bases of enzyme kinetic data taken from literature and not adjusted for the specific simulations shown here. Upon glucose depletion a rapid increase in PEP, inorganic phosphate and a gradual decrease in fructose 1,6-bisphosphate (FBP) were measured and predicted by simulation. The dynamic changes in these and other intermediate concentrations as measured in the experiments were well predicted by the kinetic model.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Lactococcus lactis
/
Glucose
/
Glicólise
/
Modelos Biológicos
Tipo de estudo:
Prognostic_studies
Idioma:
En
Revista:
Mol Biol Rep
Ano de publicação:
2002
Tipo de documento:
Article