[Psychiatric complications of corticoid therapy in the elderly over 65 years of age treated for Horton disease]. / Complications psychiatriques de la corticothérapie chez le sujet âgé de plus de 65 ans traité pour maladie de Horton.
Rev Med Interne
; 23(10): 828-33, 2002 Oct.
Article
em Fr
| MEDLINE
| ID: mdl-12428485
ABSTRACT
OBJECTIVES:
To analyse steroid psychiatric related complications in aged (> 65 years old) with temporal arteritis (TA).METHODS:
Retrospective cohort study. PATIENTS In a cohort of 126 elderly patients with a diagnosis of TA and followed with a mean period of 64 months, clinical and biological presentations, outcome and corticoid adverse effects were recorded throughout the follow-up period.RESULTS:
Twenty patients (16%), (mean age 73 +/- 7.9 years, male n = 6) exhibited corticosteroid related psychiatric complications. Symptoms appear to be dose dependent and generally begin during the first month of treatment. Psychiatric disorders were as follow mood disturbances (n = 8), depression (n = 6), mania (n = 3), anxiety neurosis (n = 2) and dementia (n = 1). Three patients were hospitalized in psychiatric units and 2 in nursing home. Psychiatric adverse affects appears to be more frequent with prednisone than prednisolone (P < 0.05).
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Coleções:
01-internacional
Contexto em Saúde:
2_ODS3
Base de dados:
MEDLINE
Assunto principal:
Psicoses Induzidas por Substâncias
/
Cefaleia Histamínica
/
Anti-Inflamatórios
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
Idioma:
Fr
Revista:
Rev Med Interne
Ano de publicação:
2002
Tipo de documento:
Article