Local treatment of tendinopathies: a comparison between tropisetron and depot corticosteroids combined with local anesthetics.
Scand J Rheumatol
; 31(6): 366-70, 2002.
Article
em En
| MEDLINE
| ID: mdl-12492253
ABSTRACT
OBJECTIVE:
To determine whether local injection of the 5-HT3-receptor antagonist, tropisetron. reduces pain in tendinopathies to the same degree as a local injection of corticosteroids in combination with local anesthetic.METHODS:
Forty patients with tendinopathies were enrolled in this randomized, observer-blind study. An injection of either 5 mg tropisetron. or 10 mg dexamethasone combined with 60 mg lidocaine was administered around the affected tendon. The effect was measured with a visual analog pain scale before the injection, after 3 hours and on each of the following 7 days, in patients with good effects also 3 months after the injection.RESULTS:
There were no significant differences between the tropisetron and the corticosteroid/anesthetic group in terms of pain at rest or on movement during the study. Both treatments were well tolerated.CONCLUSION:
Local injection of tropisetron seems to be as safe and as effective as the combination of corticosteroids and local anesthetics in the treatment of painful tendinopathies.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Antagonistas da Serotonina
/
Corticosteroides
/
Tendinopatia
/
Indóis
Tipo de estudo:
Clinical_trials
/
Diagnostic_studies
/
Etiology_studies
Limite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Scand J Rheumatol
Ano de publicação:
2002
Tipo de documento:
Article