[Hemoglobin C -- beta-thalassemia disease and homozygous beta-thalassemia in a black African family (author's transl)]. / Hémoglobine C -- beta-thalassémie et beta-thalassémie homozygote dans une famille Noire Africaine
Nouv Rev Fr Hematol
; 15(3): 343-56, 1975.
Article
em Fr
| MEDLINE
| ID: mdl-128735
ABSTRACT
The study of a Malian family has allowed to prove existence of two types of beta-thalassemia genes the beta0 gene which suppresses the synthesis of the beta chain into cis position and the beta+ gene which slows down only partially this synthesis. The difference between this two genes has been possible owing to the hemoglobin C found in this family and induced by the betaC mutated gene. The segregation of the four genes betaA, betaC, beta0 thal, and beta+ thal. has allowed to compare all the possible phenotypes deriving from the combinations by two of these allelic genes.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fenótipo
/
Talassemia
/
Hemoglobina C
Limite:
Female
/
Humans
/
Male
País/Região como assunto:
Africa
Idioma:
Fr
Revista:
Nouv Rev Fr Hematol
Ano de publicação:
1975
Tipo de documento:
Article