Expression of prolactin receptors in human liver during cholestasis of different etiology and secondary liver cancer.
Bull Exp Biol Med
; 135(6): 566-9, 2003 Jun.
Article
em En
| MEDLINE
| ID: mdl-12937675
ABSTRACT
Indirect immunoperoxidase assay and computer analysis of photographic images revealed more intensive expression of prolactin receptors in hepatocytes of women compared to men. The intensity of expression was maximum in secondary liver cancer, high in obstructive jaundice of different etiology, and less pronounced in cholelithiasis. The expression of prolactin receptors in cholangiocytes was higher than in hepatocytes and was maximum during obstructive jaundice of different etiology. Cells of secondary tumors were characterized by low expression, while distant hepatocytes most intensively expressed prolactin receptors.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Receptores da Prolactina
/
Colestase
/
Fígado
/
Neoplasias Hepáticas
Tipo de estudo:
Etiology_studies
Limite:
Adult
/
Aged
/
Animals
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Bull Exp Biol Med
Ano de publicação:
2003
Tipo de documento:
Article