Regiochemical variation in the electrophilic addition of HBr to 1-phenylprop-1-yne.
Org Biomol Chem
; 1(12): 2148-51, 2003 Jun 21.
Article
em En
| MEDLINE
| ID: mdl-12945905
ABSTRACT
The reaction of aryl alkynes with dilute methylene chloride solutions of quaternary ammonium bromide and 20% trifluoroacetic acid produces primarily the syn Markovnikov adducts of hydrogen bromide. At moderate concentrations of the bromide, the principal product is the Markovnikov anti adduct. At high concentrations of bromide, the anti-Markovnikov anti addition product predominates.
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01-internacional
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MEDLINE
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En
Revista:
Org Biomol Chem
Ano de publicação:
2003
Tipo de documento:
Article