Antihypertensive and metabolic effects of nitrendipine in non-insulin-dependent diabetes mellitus with hypertension.
J Cardiovasc Pharmacol
; 19 Suppl 2: S39-40, 1992.
Article
em En
| MEDLINE
| ID: mdl-1377303
ABSTRACT
Fifteen non-insulin-dependent diabetes mellitus hypertensive patients received nitrendipine (20-40 mg) for 24 weeks. Mean systolic and diastolic blood pressure decreased significantly from 177/102 mm Hg before treatment to 153/86 mm Hg (p less than 0.001) after treatment. Meanwhile, the heart rate, body weight, indices of glycemic control (glucose, glycosylated hemoglobin, fructosamine, and serum C peptide levels), and serum lipid fractions did not change. It is concluded that nitrendipine does not impair glucose and lipid metabolism in diabetic patients while exerting its antihypertensive effect.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Nitrendipino
/
Diabetes Mellitus Tipo 2
/
Hipertensão
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Cardiovasc Pharmacol
Ano de publicação:
1992
Tipo de documento:
Article