Renal function in preterm infants during the first five days of life: influence of maturation and early colloid treatment.
Biol Neonate
; 61(5): 308-17, 1992.
Article
em En
| MEDLINE
| ID: mdl-1391257
ABSTRACT
We measured the influence of maturation and early freshly frozen plasma infusion (FFP) on renal function (day 2 and day 5) in preterm infants in intensive care; they were divided into two groups, those with gestational ages less than 30 weeks (G less than 30) and those with gestational ages of 30-34 weeks (G 30-34). A total of 35 infants was studied. The infants were randomly assigned to one of two treatment groups, one receiving FFP, the other not, yielding four study groups; G less than 30 and no FFP (8 infants), G less than 30 and FFP (8 infants), G 30-34 and no FFP (9 infants) and G 30-34 and FFP (10 infants). The infants in the two FFP groups received FFP 10 ml/kg on days 1-3. FFP did not significantly influence creatinine clearance (CCr) or the urinary sodium excretion rate either in G less than 30 or G 30-34. CCr was significantly lower (p less than 0.001) and fractional urinary sodium excretion significantly higher (p less than 0.002) in infants of G less than 30 than in infants of G 30-34. Infants of G less than 30 had significantly higher plasma potassium concentrations (p less than 0.01) than infants of G 30-34. Despite the low CCr and the high urinary sodium excretion rate, infants of G less than 30 had stable fluid and electrolyte balance.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Envelhecimento
/
Recém-Nascido Prematuro
/
Coloides
/
Rim
Tipo de estudo:
Clinical_trials
Limite:
Humans
/
Newborn
Idioma:
En
Revista:
Biol Neonate
Ano de publicação:
1992
Tipo de documento:
Article