[Comparison of serum leptin clearance with different blood purification].
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue
; 15(12): 742-4, 2003 Dec.
Article
em Zh
| MEDLINE
| ID: mdl-14659060
ABSTRACT
OBJECTIVE:
To compare the serum Leptin clearance efficiency with different blood purification treatment.METHODS:
Thirty-one chronic end-stage renal failure hemodialysis (HD) patients (16 men, 15 women, mean age (54.0+/-11.0) years) were enrolled into the study. All the patients were treated with routine hemodialysis, the serum Leptin levels were examined before and after HD. Then they were divided into two groups, one was to be treated with hemodiafiltration (12 patients), and the other was to be treated with blood adsorption (8 patients). The same serum Leptin levels were examined before and after treatment. Serum Leptin concentration was detected by radioimmunoassay (RIA).RESULTS:
The concentration of serum Leptin was not significantly decreased after routine hemodialysis in HD patients ((11.820+/-5.507) microg/L vs. (12.255+/-5.172) microg/L, P>0.05). Leptin concentrations after hemodiafiltration and blood adsorption therapy were decreased to the levels of (29.07+/-8.56) percent and (40.29+/-8.33) percent respectively, and their curative effect was significantly different (P=0.001).CONCLUSION:
Routine hemodialysis can influence serum Leptin levels in HD patients. Hemodiafiltration and blood adsorption therapy can lower serum Leptin levels. Blood adsorption therapy is better than hemodiafiltration in the clearance of serum Leptin.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hemodiafiltração
/
Leptina
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Zh
Revista:
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue
Ano de publicação:
2003
Tipo de documento:
Article