A newly discovered verotoxin variant, VT2g, produced by bovine verocytotoxigenic Escherichia coli.
Appl Environ Microbiol
; 69(12): 7549-53, 2003 Dec.
Article
em En
| MEDLINE
| ID: mdl-14660413
ABSTRACT
A new verotoxin (VT) variant, designated vt2g, was identified from a bovine strain of verocytotoxigenic Escherichia coli (VTEC) serotype O2H25. When vt2g was aligned with published sequences of vt2 and vt variants, it exhibited the highest DNA sequence homology with vt2 and vt2c. However, vt2g was not detected by vt2-specific primers and probes, although it was partially neutralized by an antiserum to the VT2A subunit. VT2g was cytotoxic for Vero and HeLa cells and was not activated by mouse intestinal mucus. The vt2g gene was detected in 3 of 409 (0.7%) bovine VTEC strains, including serotypes O2H25, O2H45 and OntH-.
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
3_ND
Base de dados:
MEDLINE
Assunto principal:
Doenças dos Bovinos
/
Toxina Shiga II
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Escherichia coli
/
Infecções por Escherichia coli
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Appl Environ Microbiol
Ano de publicação:
2003
Tipo de documento:
Article