Co-existence of Philadelphia chromosome positive acute megakaryoblastic and B-lymphoblastic mixed blast crisis of chronic myeloid leukemia with chronic lymphocytic leukemia.
Eur J Haematol
; 72(5): 361-5, 2004 May.
Article
em En
| MEDLINE
| ID: mdl-15059073
ABSTRACT
In this study, we describe an extremely rare case of co-existence of a Philadelphia chromosome positive acute megakaryoblastic and B-lymphoblastic mixed blast crisis of chronic myeloid leukemia with chronic lymphocytic leukemia. A morphological, immunophenotypical and cytogenetic study has been performed to characterize the case and in order to identify the origin of two disorders. After the failure of the conventional therapy, the patient was treated with Imatinib with a complete hematological and cytogenetic response and a marked reduction of bone marrow fibrosis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Leucemia Linfocítica Crônica de Células B
/
Leucemia Mielogênica Crônica BCR-ABL Positiva
/
Crise Blástica
/
Leucemia Megacarioblástica Aguda
/
Linfoma de Burkitt
/
Neoplasias Primárias Múltiplas
Tipo de estudo:
Prognostic_studies
Limite:
Aged
/
Female
/
Humans
Idioma:
En
Revista:
Eur J Haematol
Ano de publicação:
2004
Tipo de documento:
Article