Sensory mechanisms: transmitters, modulators and reflexes.
Neurogastroenterol Motil
; 16 Suppl 1: 60-3, 2004 Apr.
Article
em En
| MEDLINE
| ID: mdl-15066007
ABSTRACT
The enteric nervous system in combination with inputs from parasympathetic and sympathetic nerves regulate the contractile, secretory and vasomotor activity of the gastrointestinal track via neural reflexes. Sensory elements which may be present in specialized neurones, enteroendocrine cells or mast cells detect changes in force, chemical composition or even foreign antigens. Sensory elements signal the enteric nervous system to correct these changes by altering contractile activity, secretion and blood flow. Advances have been made in understanding the sensory mechanisms that are involved in 5-hydroxytryptamine (5-HT) release from enterochromaffin cells (EC) or a model for EC cells. These advances relate to roles for ATP and its metabolites ADP and adenosine in mechanotransduction and a role for a sodium glucose cotransporter, a SGLT-like protein, in chemotransduction.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Células Receptoras Sensoriais
/
Sistema Nervoso Entérico
/
Mecanotransdução Celular
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Sistema Digestório
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Células Enterocromafins
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Neurogastroenterol Motil
Ano de publicação:
2004
Tipo de documento:
Article