Epidemiology of rabbit haemorrhagic disease virus in the United Kingdom: evidence for seasonal transmission by both virulent and avirulent modes of infection.
Epidemiol Infect
; 132(3): 555-67, 2004 Jun.
Article
em En
| MEDLINE
| ID: mdl-15188725
ABSTRACT
Rabbit haemorrhagic disease virus (RHDV) has killed many millions of wild rabbits in Europe and Australia, but has had little impact in the United Kingdom, despite outbreaks having occurred since 1994. High seroprevalence detected in the absence of associated mortality had suggested the presence of an endemic non-pathogenic strain which may be 'protecting' UK populations. Following the first detailed field study of RHDV epidemiology in the United Kingdom, using mark-recapture with serum sampling, we report that RHDV caused highly prevalent persistent infection in seropositive rabbits in the absence of associated mortality. Furthermore the virus strains responsible could not be distinguished phylogenetically from known pathogenic isolates, and were clearly very different from the only previously identified non-pathogenic strain of RHDV. These findings suggest that many--perhaps most--strains of RHDV may be propagated through both 'pathogenic' and 'non-pathogenic' modes of behaviour. Transmission occurred predominantly during and just after the breeding season.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vírus da Doença Hemorrágica de Coelhos
/
Transmissão de Doença Infecciosa
/
Transtornos Hemorrágicos
Tipo de estudo:
Prognostic_studies
/
Screening_studies
Limite:
Animals
País/Região como assunto:
Europa
Idioma:
En
Revista:
Epidemiol Infect
Ano de publicação:
2004
Tipo de documento:
Article