The use of a "liquid" electrode in hepatic electrolysis.
J Surg Res
; 120(2): 272-7, 2004 Aug.
Article
em En
| MEDLINE
| ID: mdl-15234223
ABSTRACT
BACKGROUND:
The use of direct current electrolysis as a local nonthermal ablative technique for colorectal liver metastases promises to be a simple, safe, and effective therapy. Under general anesthesia, electrolysis is presently limited to tumors smaller than 5 cm, due to the protracted nature of its administration. In an attempt to enhance the effect of electrolysis, a direct current was passed through a preinjected bolus of acetic acid.METHODS:
The effect of a combination of electrolysis and an injection of acetic acid was tested in the liver of eight normal pigs. The volumes of necrosis caused were analyzed.RESULTS:
Acetic acid independently produced a volume of necrosis but did not provide a volumetric or rate advantage when used in combination with a direct current. Statistically, the only main effect on the volume of necrosis was a result of electrolysis.CONCLUSION:
The use of 50% acetic acid to augment the efficacy of direct current electrolysis cannot be recommended.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ácido Acético
/
Eletrodos
/
Eletrólise
/
Fígado
Limite:
Animals
Idioma:
En
Revista:
J Surg Res
Ano de publicação:
2004
Tipo de documento:
Article