Surfactant protein A and D (SP-A, AP-D) levels in patients with septic ARDS.
Res Commun Mol Pathol Pharmacol
; 111(5-6): 245-51, 2002.
Article
em En
| MEDLINE
| ID: mdl-15244040
ABSTRACT
The levels of surfactant protein-A (SP-A) and surfactant protein-D (SP-D) in the serum of patients with septic acute respiratory distress syndrome (ARDS) were determined. Patients with sepsis without ARDS were examined as controls. The mean serum SP-A level in the former group was 37.6 +/- 16.2 ng/ml and in the latter group was 31.8 +/- 9.6 ng/ml. The difference between the two groups was not statistically significant. The maximum serum SP-D level was 83.0 +/- 33.9 ng/ml in the control group of patients without ARDS, and 476.3 +/- 391.2 ng/ml in the patients with ARDS. The level in the latter population was significantly higher than that in the former population. No significant correlation was observed between the SP-A and SP-D levels. These results suggest that the serum SP-D levels may serve as a good diagnostic indicator of ARDS in patients with sepsis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síndrome do Desconforto Respiratório
/
Sepse
/
Proteína A Associada a Surfactante Pulmonar
/
Proteína D Associada a Surfactante Pulmonar
Tipo de estudo:
Etiology_studies
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Res Commun Mol Pathol Pharmacol
Ano de publicação:
2002
Tipo de documento:
Article