[Biotransformation of dehydroepiandrosterone by hairy root cultures of Anisodus tanguticus].
Yao Xue Xue Bao
; 39(6): 445-8, 2004 Jun.
Article
em Zh
| MEDLINE
| ID: mdl-15491103
ABSTRACT
AIM:
To modify the structure of dehydroepiandrosterone (DHEA).METHODS:
Using hairy root cultures of Anisodus tanguticus to perform biotransformation of DHEA, using chromatographic and spectral techniques to isolate and identify the products.RESULTS:
(1) The MS medium without plant hormone was suitable for the growth of the hairy root. (2) DHEA was converted into five products androst-4-ene-3, 17-dione (I); 6alpha-hydroxyandrost-4-ene-3, 17-dione (II); 6alpha, 17beta-dihydroxyandrost-4-ene-3-one (III); androst-4-ene-3, 6, 17-trione (IV) and 17beta-hydroxyandrost-4-ene-3-one (V).CONCLUSION:
It is the first time to use hairy root cultures of Anisodus tanguticus for the biotransformation of DHEA and five DHEA-related compounds were obtained.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Plantas Medicinais
/
Desidroepiandrosterona
/
Solanaceae
/
Androstenodiona
/
Androstenos
Idioma:
Zh
Revista:
Yao Xue Xue Bao
Ano de publicação:
2004
Tipo de documento:
Article