Optimization of 13C direct detection NMR methods.
J Biomol NMR
; 30(2): 175-9, 2004 Oct.
Article
em En
| MEDLINE
| ID: mdl-15557804
ABSTRACT
(13)C-detected experiments are still limited by their inherently lower sensitivity, as compared to the equivalent (1)H-detected experiments. Improving the sensitivity of (13)C detection methods remains a significant area of NMR research that may provide better means for studying large macromolecular systems by NMR. In this communication, we show that (13)C-detected experiments are less sensitive to the salt concentration of the sample solution than (1)H-detected experiments. In addition, acquisition can be started with anti-phase coherence, resulting in higher sensitivity due to the elimination of the final INEPT transfer step.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Espectroscopia de Ressonância Magnética
Tipo de estudo:
Diagnostic_studies
Idioma:
En
Revista:
J Biomol NMR
Ano de publicação:
2004
Tipo de documento:
Article