Ultrastructural analysis of the interactions between Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica and human tracheal epithelial cells.
Microb Pathog
; 38(1): 41-6, 2005 Jan.
Article
em En
| MEDLINE
| ID: mdl-15652294
ABSTRACT
Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica are respiratory pathogens that colonize the respiratory tract of their host after adhesion to the respiratory epithelium. Presently, the intracellular fate of these bacteria in human tracheal epithelial cells was compared by use of transmission electron microscopy. The three species, even when cytotoxic, were taken-up by epithelial cells. Although, some intracellular bacteria appeared morphologically intact and survived a few days inside epithelial cells, most of them appeared quickly degraded, phenomenon which was associated with an intense cell metabolic activity. Even cytotoxic Bordetella species is ultimately killed by human epithelial cells.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Traqueia
/
Aderência Bacteriana
/
Bordetella pertussis
/
Bordetella bronchiseptica
/
Bordetella parapertussis
/
Células Epiteliais
Limite:
Humans
Idioma:
En
Revista:
Microb Pathog
Ano de publicação:
2005
Tipo de documento:
Article