[After your heart arrest, would you like to test a medicinal elixir?]. / Après votre arrêt cardiaque, vous prendrez bien un peu d'élixir de (sur)vie?
Rev Med Suisse
; 1(6): 448-51, 2005 Feb 09.
Article
em Fr
| MEDLINE
| ID: mdl-15786650
ABSTRACT
So far, cardiac arrest is still associated with high mortality or severe neurological disability in survivors. At the tissue level, cardiac arrest results into an acute condition of generalized hypoxia. A better understanding of the pathophysiology of ischemia-reperfusion and of the inflammatory response that develops after cardiac arrest could help to design novel therapeutic strategies in the future. It seems unlikely that a single drug, acting as a <<magic bullet>>, might be able to improve survival or neurological prognosis. Lessons learned from pathophysiological mechanisms rather indicate that combined therapies, involving thrombolysis, neuroprotective agents, antioxidants and anti-inflammatory molecules, together with temperature cooling, might represent helpful strategies to improve patient's outcome after cardiac arrest.
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Coleções:
01-internacional
Contexto em Saúde:
6_ODS3_enfermedades_notrasmisibles
Base de dados:
MEDLINE
Assunto principal:
Parada Cardíaca
Limite:
Humans
Idioma:
Fr
Revista:
Rev Med Suisse
Ano de publicação:
2005
Tipo de documento:
Article