Adrenal failure followed by status epilepticus and hemolytic anemia in primary antiphospholipid syndrome.
Thromb J
; 3(1): 6, 2005 Apr 18.
Article
em En
| MEDLINE
| ID: mdl-15836793
ABSTRACT
We report on a 14 year old boy who presented with the symptoms abdominal pain, fever and proteinuria. A hematoma in the region of the right pararenal space was diagnosed. Prothrombin time and activated partial thromboplastin time were prolonged, lupus anticoagulant and anticardiolipin antibodies were positive and serum cortisol was normal. Ten days after admission the boy suddenly suffered generalized seizures due to low serum sodium. As well, the patient developed hemolytic anemia, acute elevated liver enzymes, hematuria and increased proteinuria. At this time a second hemorrhage of the left adrenal gland was documented. Adrenal function tests revealed adrenal insufficiency. We suspected microthromboses in the adrenals and secondary bleeding and treated the boy with hydrocortisone, fludrocortisone and phenprocoumon. CONCLUSION:
Adrenal failure is a rare complication of APS in children with only five cases reported to date. As shown in our patient, this syndrome can manifest in a diverse set of simultaneously occurring symptoms.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Thromb J
Ano de publicação:
2005
Tipo de documento:
Article