Differences in the DNA sequences in the upstream attenuator region of erm(A) in clinical isolates of Streptococcus pyogenes and their correlation with macrolide/lincosamide resistance.
Antimicrob Agents Chemother
; 49(7): 3070-2, 2005 Jul.
Article
em En
| MEDLINE
| ID: mdl-15980403
ABSTRACT
The regulatory regions of 52 erm(A) [formerly erm(TR)] clinical Streptococcus pyogenes isolates were studied. Differences in the upstream regulatory region of erm(A) correlated with macrolide/lincosamide resistance patterns. Nine macrolide/lincosamide/streptogramin B-resistant isolates had changes in the leader sequence of erm(A) including base changes, insertions, or deletions. Isolates were also emm typed.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Streptococcus pyogenes
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Proteínas de Bactérias
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Sinais Direcionadores de Proteínas
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Regulação Bacteriana da Expressão Gênica
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Farmacorresistência Bacteriana
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Metiltransferases
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Mutação
Limite:
Humans
Idioma:
En
Revista:
Antimicrob Agents Chemother
Ano de publicação:
2005
Tipo de documento:
Article