[Correlation between platelet count and CA-125 in ovarian cancer]. / Znaczenie kliniczne poziomu plytek krwi w raku jajnika.
Ginekol Pol
; 76(3): 187-94, 2005 Mar.
Article
em Pl
| MEDLINE
| ID: mdl-16018136
ABSTRACT
OBJECTIVE:
To determine whether a correlation between platelet count and CA-125 exists, and to compare the mean levels of CA-125 in groups with normal and elevated platelet counts.DESIGN:
A retrospective analysis of the medical records concerning to 31 ovarian cancer inpatients, treated 1998-2002 with primary surgery and subsequent platinum-based chemotherapy at the Division of Gynecology, Department of Perinatology and Gynecology, University Medical School Poznan. MATERIALS ANDMETHODS:
137 serum and whole blood samples collected from 31 ovarian cancer patients during their consecutive hospital stays.RESULTS:
There was a positive, moderate (r = 0.49) and highly significant (p < 0.0000001) correlation between platelet count and CA-125 levels. Thrombocytosis occurred in 45% patients before treatment, and in none when the 6th course of chemotherapy was given. In the thrombocytosis group, an average CA-125 level (913.5 U/ml) was significantly higher (p < 0.00001) then in the group with normal platelet count (103.7 U/ml).CONCLUSIONS:
Platelet count and CA-125 levels do correlate in blood samples taken from ovarian cancer patients at the same time.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Ovarianas
/
Contagem de Plaquetas
/
Trombocitose
/
Antígeno Ca-125
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Middle aged
País/Região como assunto:
Europa
Idioma:
Pl
Revista:
Ginekol Pol
Ano de publicação:
2005
Tipo de documento:
Article