Systemic interleukin-10 concentrations do not alter between the first and second trimester in normal pregnancy.
Arch Gynecol Obstet
; 273(3): 150-1, 2005 Dec.
Article
em En
| MEDLINE
| ID: mdl-16021491
ABSTRACT
BACKGROUND:
Interleukin 10 (IL-10) is involved in normal fecundity and systemic IL-10 changes during gestation might reflect an immunologic shift at the maternal-fetal interface.METHODS:
Serum IL-10 levels were measured in the first and second trimester of uncomplicated pregnancy in 32 women. The low interassay coefficient of variation of the low adjustor of the IL-10 assay (5.2%) enabled us to detect IL-10 concentrations between 0.50 pg/ml and 4.0 pg/ml.RESULTS:
There was no statistically significant difference between serum IL-10 levels in the first trimester (median 1.10; range 0.53-4.60 pg/ml) and second trimester (median 1.05; range 0.64-3.30 pg/ml).CONCLUSION:
IL-10 is not systemically activated to a detectable degree between the first and second trimester of normal pregnancy.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Gravidez
/
Interleucina-10
Limite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Arch Gynecol Obstet
Ano de publicação:
2005
Tipo de documento:
Article