Rosai-Dorfman disease: successful long-term results by combination chemotherapy with prednisone, 6-mercaptopurine, methotrexate, and vinblastine: a case report.
Int J Surg Pathol
; 13(3): 285-9, 2005 Jul.
Article
em En
| MEDLINE
| ID: mdl-16086087
ABSTRACT
Sinus histiocytosis with massive lymphadenopathy (SHML), also known as Rosai-Dorfman disease (RDD), is a rare clinicopathologic entity of unknown etiology. The majority of patients do not require treatment, demonstrating spontaneous resolution or stable disease. However, in some cases the disorder runs a progressive course and/or threatens vital structures and functions, which dictates some form of intervention. It is not clear what constitutes the best approach for those cases. We report on a girl with an extensive and progressive form of the disease who was cured with combination chemotherapy, showing no evidence of recurrence after a follow-up of 5.5 years.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Histiocitose Sinusal
/
Quimioterapia Combinada
/
Anti-Inflamatórios
/
Antimetabólitos
Limite:
Adolescent
/
Female
/
Humans
Idioma:
En
Revista:
Int J Surg Pathol
Ano de publicação:
2005
Tipo de documento:
Article