ATM promoter analysis in childhood lymphoid malignancies: a brief communication.
Leuk Res
; 30(3): 335-7, 2006 Mar.
Article
em En
| MEDLINE
| ID: mdl-16125772
ATM promoter hypermethylation has been recently reported in adult carcinomas, but no information is available concerning the methylation status of ATM gene promoter in childhood B-precursor acute lymphoblastic leukaemia (ALL). Furthermore, involvement of somatic ATM promoter mutations in cancer is not known. We report a complete ATM gene promoter analysis in 74 childhood lymphoid malignancies.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Linfoma de Burkitt
/
Regiões Promotoras Genéticas
/
Proteínas Serina-Treonina Quinases
/
Mutação Puntual
/
Proteínas de Ciclo Celular
/
Metilação de DNA
/
Proteínas Supressoras de Tumor
/
Proteínas de Ligação a DNA
/
Leucemia-Linfoma Linfoblástico de Células Precursoras
Limite:
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Leuk Res
Ano de publicação:
2006
Tipo de documento:
Article