New cytotoxic-antineoplastic prenyl-1,2-naphthohydroquinone derivatives.
Bioorg Med Chem
; 13(24): 6645-50, 2005 Dec 15.
Article
em En
| MEDLINE
| ID: mdl-16169232
Several new prenylnaphthohydroquinone derivatives have been prepared through the Diels-Alder condensation between alpha-myrcene and 1,2-benzoquinone and evaluated for their cytotoxic activity against A-549, HT-29 and MB-231 cultured cell lines. All of them have shown GI50 values in the microM level.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Prenilamina
/
Naftoquinonas
/
Antineoplásicos
Limite:
Humans
Idioma:
En
Revista:
Bioorg Med Chem
Ano de publicação:
2005
Tipo de documento:
Article