[Major hepatectomy for metastasis of colorectal cancer improves survival in the elderly]. / Hépatectomie majeure pour métastases de cancers colorectaux chez le sujet âgé.
Ann Chir
; 130(9): 562-5, 2005 Oct.
Article
em Fr
| MEDLINE
| ID: mdl-16202886
ABSTRACT
OBJECTIVE:
Assessing impact of major liver resection (LR) for hepatic metastasis of colorectal cancer (HMCC) on post operative courses and long term survival in the elderly. PATIENTS ANDMETHOD:
Thirty-three consecutive patients aged over 70 years-old were treated in our institution for up to 3 resectable metachronous HMCC. Fifteen patients had major LR (9 right hepatectomy, 3 extended right hepatectomy, 3 left hepatectomy) without pre or postoperative chemotherapy (group 1) and 18 patients were exclusively treated by chemotherapy (group 2) because of high ASA score (ASA 3) or patients refusal.RESULTS:
No patients died of another cause that colorectal cancer disease during observation time. All patients of group 2 died during observation time. Post operative mortality and morbidity of group 1 were respectively 0% and 33%. Survival at 1 and 2 years of group 1-2 were respectively 73-50% (P=0,04) and 47-15% (P=0,05). Median survival of group 1 and 2 were respectively 22 and 12 months (P=0,03).CONCLUSIONS:
Major LR for HMCC could be proposed regardless the age. High ASA score, multiple (more than 4) metastasis location, evolutive disease could justify an exclusive medical approach.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Colorretais
/
Hepatectomia
/
Neoplasias Hepáticas
Tipo de estudo:
Prognostic_studies
Limite:
Aged
/
Female
/
Humans
/
Male
Idioma:
Fr
Revista:
Ann Chir
Ano de publicação:
2005
Tipo de documento:
Article