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Frequency and determinants of the postthrombotic syndrome after venous thromboembolism.
Kahn, Susan R.
Afiliação
  • Kahn SR; Centre for Clinical Epidemiology and Community Studies, SMBD Jewish General Hospital, and Department of Medicine, McGill University, Montreal, Quebec, Canada. susan.kahn@mcgill.ca
Curr Opin Pulm Med ; 12(5): 299-303, 2006 Sep.
Article em En | MEDLINE | ID: mdl-16926641
ABSTRACT
PURPOSE OF REVIEW Postthrombotic syndrome (PTS) is the most common complication of deep venous thrombosis (DVT). Identifying which patients are at high risk of developing PTS would help improve the management of patients with DVT and allow physicians to provide patients with individualized information on their expected prognosis. This review discusses the knowledge gained from key studies over the last decade on the incidence and determinants of PTS, with special emphasis on published studies from the last 2 years. RECENT

FINDINGS:

About a third to half of DVT patients will develop PTS, in most cases within 1-2 years of acute DVT. Important risk factors for PTS appear to be ipsilateral recurrence of DVT, poor quality of initial anticoagulation for the treatment of DVT and increased body mass index.

SUMMARY:

Preventing DVT recurrence by providing adequate intensity and duration of anticoagulation for the initial DVT and using effective thromboprophylaxis in high-risk settings is likely to reduce the frequency of PTS. Despite some advances in identifying risk factors for PTS, however, it is still not possible to reliably predict an individual patient's risk of developing PTS after an episode of DVT. Further studies of clinical determinants and biological markers of increased risk of PTS are needed to ultimately improve long-term prognosis after DVT.
Assuntos
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Coleções: 01-internacional Contexto em Saúde: 2_ODS3 Base de dados: MEDLINE Assunto principal: Síndrome Pós-Flebítica / Trombose Venosa Tipo de estudo: Etiology_studies / Incidence_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Curr Opin Pulm Med Ano de publicação: 2006 Tipo de documento: Article
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Coleções: 01-internacional Contexto em Saúde: 2_ODS3 Base de dados: MEDLINE Assunto principal: Síndrome Pós-Flebítica / Trombose Venosa Tipo de estudo: Etiology_studies / Incidence_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Curr Opin Pulm Med Ano de publicação: 2006 Tipo de documento: Article