[Advances in the study of steroidogenic acute regulatory protein].
Zhonghua Nan Ke Xue
; 12(8): 733-6, 2006 Aug.
Article
em Zh
| MEDLINE
| ID: mdl-16970168
ABSTRACT
The steroidogenic acute regulatory (StAR) protein is an essential component in the regulation of steroid biosynthesis in adrenal and gonadal cells. The StAR protein has a high tissue specificity, located on the mitochondrial membranes of some relative cells. It regulates the transfer of cholesterin from extracellular into intracellular and plays a dominant role in steroidogenic synthesis. Recent studies have also shown that the transcription and expression of StAR are modulated not only through the cAMP-PKA dependent pathway, but also by multiple hormones and cytokines, which contributes to the regulation of cholesterin synthesis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fosfoproteínas
Limite:
Animals
/
Humans
Idioma:
Zh
Revista:
Zhonghua Nan Ke Xue
Ano de publicação:
2006
Tipo de documento:
Article