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Efficacy of DNA immunization with F and G protein genes of Nipah virus.
Wang, Xijun; Ge, Jinying; Hu, Sen; Wang, Qinghua; Wen, Zhiyun; Chen, Hualan; Bu, Zhigao.
Afiliação
  • Wang X; National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Science, Harbin 150001, P.R. China.
Ann N Y Acad Sci ; 1081: 243-5, 2006 Oct.
Article em En | MEDLINE | ID: mdl-17135518
We investigated the antibody response of DNA immunization with two mammalian codon optimized envelope glycoprotein genes, F and G, of Nipah virus in a mouse model. The results indicated that G gene immunization elicited more significant specific serum IgG response and neutralization antibody response than F gene did, suggesting that the G gene DNA immunization is a potential vaccine strategy against Nipah virus.
Assuntos
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Coleções: 01-internacional Contexto em Saúde: 2_ODS3 / 4_TD Base de dados: MEDLINE Assunto principal: Proteínas Virais / Vacinas Virais / Vacinas de DNA / Vírus Nipah / Infecções por Henipavirus Limite: Animals / Humans Idioma: En Revista: Ann N Y Acad Sci Ano de publicação: 2006 Tipo de documento: Article
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Coleções: 01-internacional Contexto em Saúde: 2_ODS3 / 4_TD Base de dados: MEDLINE Assunto principal: Proteínas Virais / Vacinas Virais / Vacinas de DNA / Vírus Nipah / Infecções por Henipavirus Limite: Animals / Humans Idioma: En Revista: Ann N Y Acad Sci Ano de publicação: 2006 Tipo de documento: Article