Major brain lesions by intrauterine herpes simplex virus infection: MRI contribution.
Prenat Diagn
; 27(1): 81-4, 2007 Jan.
Article
em En
| MEDLINE
| ID: mdl-17154224
ABSTRACT
The majority of neonatal Herpes Simplex Virus (HSV) infections are acquired at birth as a consequence of direct fetal contact with the infected birth canal or through an ascending infection after premature rupture of the amniotic membranes. Intrauterine transmission of HSV infection from mother to the fetus is rare; in only 5% of the cases it occurs from haematogenous transplacental dissemination. We present a case of transplacental intrauterine HSV infection after a primary maternal HSV infection in the first trimester of pregnancy. The diagnosis was assessed by viral culture and serologic tests. Ultrasound imaging revealed fetal brain damage in the third trimester. Finally, the MRI showed the devastating extensiveness of the HSV infection, which was beyond the expectation based on the ultrasound images.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Complicações Infecciosas na Gravidez
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Encéfalo
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Imageamento por Ressonância Magnética
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Herpes Genital
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Transmissão Vertical de Doenças Infecciosas
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
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Female
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Humans
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Male
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Pregnancy
Idioma:
En
Revista:
Prenat Diagn
Ano de publicação:
2007
Tipo de documento:
Article