Childhood convulsive status epilepticus: epidemiology, management and outcome.
Acta Neurol Scand
; 115(4 Suppl): 21-4, 2007 Apr.
Article
em En
| MEDLINE
| ID: mdl-17362272
ABSTRACT
Convulsive status epilepticus (CSE) in childhood is a medical emergency and its aetiology and outcome mean that it should be studied separately from adult CSE. The incidence in developed countries is between 17 and 23/100,000 with a higher incidence in younger children. Febrile CSE is the commonest single group with a good prognosis in sharp distinction to CSE related to central nervous system infections which have a high mortality. The aim of treatment is to intervene at 5 min and studies indicate that intravenous (i.v.) lorazepam may be a better first-line treatment than rectal diazepam and i.v. phenytoin a better second-line treatment than rectal paraldehyde. An epidemiological study strongly supports the development of prehospital treatment with buccal midazolam becoming a widely used but unlicensed option in the community. More than two doses of benzodiazepines increase the rate of respiratory depression without obvious benefit. The 1 year recurrence rate is 17% and the hospital mortality is about 3%.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pediatria
/
Estado Epiléptico
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Resultado do Tratamento
Tipo de estudo:
Observational_studies
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Prognostic_studies
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Risk_factors_studies
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Screening_studies
Limite:
Adolescent
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Female
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Humans
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Male
Idioma:
En
Revista:
Acta Neurol Scand
Ano de publicação:
2007
Tipo de documento:
Article