[A case of meningeal carcinomatosis from lung cancer successfully treated with aggressive multimodal therapy].
Nihon Kokyuki Gakkai Zasshi
; 45(3): 267-71, 2007 Mar.
Article
em Ja
| MEDLINE
| ID: mdl-17419441
ABSTRACT
A 44-year-old man was admitted to our hospital because of brain metastasis and intrapulmonary exacerbation of lung adenocarcinoma. Systemic chemotherapy (PAC + CBDCA) was administered, but neurological symptoms (muscle weakness of limbs and disorientation) appeared. Lumbar puncture and enhanced MRI of lumber vertebrae revealed meningeal carcinomatosis. MTX 20 mg/week (+ Ara-C 40 mg/week) was injected into the meningeal space. There was a clear improvement in the neurological symptoms, but it did not last long. Meningeal injection was performed 7 times. Whole-brain and whole-marrow radiation along with systemic chemotherapy gave a marked improvement in the symptoms and in the metastatic shadow on the chest CT scan.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Medula Óssea
/
Adenocarcinoma
/
Protocolos de Quimioterapia Combinada Antineoplásica
/
Irradiação Craniana
/
Neoplasias Pulmonares
/
Neoplasias Meníngeas
Limite:
Adult
/
Humans
/
Male
Idioma:
Ja
Revista:
Nihon Kokyuki Gakkai Zasshi
Ano de publicação:
2007
Tipo de documento:
Article