In dementia with Lewy bodies, Braak stage determines phenotype, not Lewy body distribution.
Neurology
; 69(4): 356-9, 2007 Jul 24.
Article
em En
| MEDLINE
| ID: mdl-17646627
ABSTRACT
We used an autopsy series to determine whether the newest dementia with Lewy bodies (DLB) consensus pathologic classification correlates with premortem diagnosis of DLB. Neocortical sections from a total of 95 cases with Lewy bodies were stained with alpha-synuclein antibodies. We assigned cases according to the DLB consensus' categories and found a significant association with the premortem clinical diagnosis of DLB. Clinical diagnosis of DLB, however, depended on the presence of low Alzheimer disease pathology (by Braak staging) rather than on Lewy body distribution.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Encéfalo
/
Corpos de Lewy
/
Doença por Corpos de Lewy
/
Neurônios
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
Neurology
Ano de publicação:
2007
Tipo de documento:
Article