Long-term prognosis for infants after massive fetomaternal hemorrhage.
Obstet Gynecol
; 110(2 Pt 1): 256-60, 2007 Aug.
Article
em En
| MEDLINE
| ID: mdl-17666598
ABSTRACT
OBJECTIVE:
To evaluate the fetal, neonatal, and long-term prognosis of massive fetomaternal hemorrhage (20 mL or more).METHODS:
This series includes all patients with Kleihauer test values of 40 per 10,000 or higher over an 8-year period at two university hospitals. We examined obstetric, neonatal, and subsequent outcome data for the children.RESULTS:
During the study period, 48 patients had massive fetomaternal hemorrhage (crude incidence 1.1 per 1,000; corrected incidence for Rh-negative women 4.6 per 1,000). Six fetal deaths were observed, representing 1.6% of all fetal deaths during the period. Nine newborns (18.7%) were transferred to neonatal intensive care unit (NICU) and five (10.4%) had transfusions. Fetomaternal hemorrhages of 20 mL/kg or more significantly increased the risk of fetal death, induced preterm delivery, transfer to NICU, and neonatal anemia requiring transfusion. Long-term follow-up was not associated with neurological sequelae (0%, 95% confidence interval 0.0-11.6%).CONCLUSION:
When the transfused volume equals or exceeds 20 mL/kg, massive fetomaternal hemorrhage may lead to severe prenatal or neonatal complications. LEVEL OF EVIDENCE III.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Morte Fetal
/
Transfusão Feto-Materna
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
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Child
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Child, preschool
/
Female
/
Humans
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Infant
/
Newborn
/
Pregnancy
Idioma:
En
Revista:
Obstet Gynecol
Ano de publicação:
2007
Tipo de documento:
Article