PIP2--the master key.
Neuron
; 55(4): 537-8, 2007 Aug 16.
Article
em En
| MEDLINE
| ID: mdl-17698006
ABSTRACT
The function of inwardly rectifying K+ (Kir) channels is highly diverse and therefore is tightly regulated by various environmental factors. In their article in this issue of Neuron, Rapedius et al. recognize a conserved structural mechanism for Kir channels gating by both pH and PIP2. In light of these findings and accumulated knowledge, PIP2 is suggested to have a common coregulatory role in the gating of Kir channels by all their soluble modulators.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ativação do Canal Iônico
/
Fosfatidilinositol 4,5-Difosfato
/
Canais de Potássio Corretores do Fluxo de Internalização
Limite:
Animals
Idioma:
En
Revista:
Neuron
Ano de publicação:
2007
Tipo de documento:
Article